Enhancing Radioiodine Incorporation Into Radio Iodine Refractory Thyroid Cancer With MAPK Inhibition (ERRITI): A Single-Center Prospective Two-Arm Study
نویسندگان
چکیده
Ziel/Aim Restoration of iodine incorporation (redifferentiation) was achieved in previously radioiodine-refractory, unresectable thyroid carcinoma by mitogen-activated protein kinase (MAPK) inhibition. However, redifferentiation unsatisfactory BRAFV600E mutated (BRAF-MUT) thus far. Here we assess safety and efficacy therapy through genotype-guided MAPK-modulation patients with BRAF-MUT or wild type (BRAF-WT) radioiodine-refractory carcinoma.
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ژورنال
عنوان ژورنال: Nuklearmedizin-nuclear Medicine
سال: 2022
ISSN: ['2567-6407', '0029-5566']
DOI: https://doi.org/10.1055/s-0042-1745942